A smarter way to support gut health

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100% spore-based probiotic

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Supports gut reconditioning

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Clinically tested to maintain a healthy gut microbiome

  • Vegan/Vegetarian

  • Non-GMO

  • Gluten-Free

  • Free From 9 Major Allergens

  • Made In The U.S. With Globally Sourced Ingredients

    Meet Mega SporeBiotic

    100% spore-based, 5-strain probiotic designed to survive the journey through digestion.

    Resilient Bacillus spores help support a healthy gut barrier, promote microbial diversity, and fuel a more balanced, resilient gut microbiome.

    Better research. Real results.

    Mega SporeBiotic provided relief for occasional abdominal discomfort and supported elimination and digestive health in study subjects.

    Ten peer-reviewed studies found that Mega SporeBiotic promotes:

    Greater microbial diversity

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    Health-supportive gut bacterial growth (and thus, short-chain fatty acid production)*

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    Helps maintain a healthy balance of naturally occurring flora*

    Robust whole body benefits

    • Promotes microbial diversity
    • Antioxidant producing
    • Supports the gut barrier/lining
    • Promotes immune function
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    The spore advantage

    Bacillus spores stay dormant in harsh conditions, then activate where they're needed.

    Dormant

    Protected by a natural spore shell, they survive stomach acid, heat & shelf storage

    Active

    Reach the intestines and shift to their active,vegetative form

    Recondition

    Promote microbial diversity & key species with high survivability

    Dosing

    Week 1: 1 capsule every other day.

    Week 2: 1 capsule per day.

    Week 3+: 2 capsules per day, with food.

    Or as recommended by your healthcare practitioner.

      Conventional Probiotics
    STRAIN RESILIENCE
    EXCEPTIONAL SURVIVAL
    QUORUM SENSING MODE OF ACTION
    MICROBIOME RECONDITIONING
    REAL WORLD EVIDENCE (300 PARTICIPANTS)

    Looking for More Effective Probiotics? Switch To Spore

    Microbiome Labs was first in the market with spore-based probiotics.

    We continue to lead with 10 peer-reviewed efficacy studies.

    How Does Spore-Based Promote a More Diverse Microbiome

    Standard Lactobacillus/ Bifidobacerium RESEED

    Probiotics can die from stomach acid or heat exposure

    Function by multiplying their own strain type

    Can worsen bloating and gas in some individuals

    Spore based Probiotics RECONDITION

    Designed to maintain efficacy and survivability throughout the Gl tract

    Encourage the growth of other keystone bacteria (like butyrate) for a flourishing microbiome and the nutrients your body needs to thrive

    At a glance

    MegaSporeBiotic is a probiotic blend of 5 Bacillus spores that have been shown to maintain healthy gut barrier and immune function. The bi-phasic life cycle of the Bacillus spores allows them to remain dormant in harsh environments until they reach more favorable environments like the human gastrointestinal tract.

    Once inside the large intestine, these dormant spores can change into their active, vegetative forms and begin colonizing in the gut. This unique probiotic blend aims to RECONDITION the gut instead of reseeding with probiotic strains that cannot survive digestion or colonize the gut. MegaSporeBiotic has quickly become a household favorite among health practitioners and consumers alike.

    Ingredients and formula

    With the launch of MegaSporeBiotic", Microbiome Labs completely disrupted the probiotic industry, shifting the focus from reseeding to reconditioning the gut microbiome with the help of Bacillus spores.

    Collapsible content

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    Bacillus Licheniformis

    Produces proteases that aid protein digestion Produces full spectrum of B vitamins

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    Bacillus Indicus HU36

    Produces carotenoids: lycopene, astaxanthin, beta-carotene, and lutein

    Produces quinols and vitamins

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    Bacillus Subtilis HU58

    Produces nattokinase and vitamin K2 Supports healthy GALT development

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    Bacillus Clausii

    Supports immune function

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    Bacillus Coagulans

    Produces L+ optical form of lactic acid Supports immune function

    5 researched bacillus strains to support:

    • Microbial diversity
    • Antioxidant production
    • Gut barrier strength
    • Immune function

    Backed by 10 clinical studies

    In 60 days, Mega SporeBiotic provided relief for occasional abdominal discomfort and supported elimination and digestive health.